How to Make Homemade Weed Killer

Key takeaways
Horticultural vinegar (20%+ acetic acid) kills on contact within 24 hours, but also kills grass.
Corn gluten meal is the only grass-safe option on this list that acts as a pre-emergent.
Salt persists in soil for months to several years. Only use salt-based recipes on driveways and hardscapes, not in garden beds or lawns
How to Make Homemade Weed Killer

Making a homemade weed killer is cheaper than most store-bought options and avoids synthetic chemicals, but the recipe and timing matter more than most people realize. The strongest homemade option, horticultural vinegar with salt and dish soap, can kill most weeds within 24 hours, but it also kills your grass.

If you need a grass-safe, low‑toxicity product that helps prevent new weeds, corn gluten meal is the only option here. For established weeds in your lawn, Lawn Love’s local weed control pros can handle the hard cases while you maintain prevention at home.

How homemade weed killers work

Most DIY weed killer recipes kill weeds through one of 3 mechanisms:

  • Contact damage: Acetic acid (vinegar) and alcohol rupture cell walls on contact, drying out leaves and stems. Roots are usually unaffected, so perennial weeds often regrow.
  • Soil disruption: Salt, baking soda, and borax each change soil chemistry in different ways. They can raise pH, interfere with nutrient uptake, or build up toxic mineral levels, which can have lasting effects on nearby plants.
  • Pre-emergent prevention: Corn gluten meal inhibits root formation in germinating seeds. It only works before weeds sprout, not on established plants.

Jessica Mercer, PhD, horticulturist at Plant Addicts in Omaha, Nebraska, says there’s a major limitation to these contact sprays.

“Homemade remedies typically do not kill perennials with deep taproots, like dandelions, dock, and thistle, or established woody shrubs and vines,” she says. “If sprayed on the leaves, the solution may burn the foliage but it will not move into the root system and kill the plant like a systemic herbicide does. Deep-rooted perennials and woody plants usually come back.”

To deal with these stubborn plants, Mercer recommends a different approach.

“For deep-rooted perennial weeds, I recommend repeatedly removing the top growth by mowing, pulling, or smothering to weaken the root system over time. If the weed is woody or invasive, physically removing the roots by hand digging is usually the most effective approach.”

TypeWhen to applyHow it works
Pre-emergentBefore weed seeds germinate (early spring)Prevents root formation in sprouting seeds
Post-emergentAfter weeds are visibleKills existing plant tissue on contact or systemically

Which recipe is right for your situation?

RecipeEffectivenessSafe for grass?Best for
Vinegar + salt solutionHighNoDriveway cracks, pavers, and young annual broadleaf weeds
Corn gluten mealLow to mediumYesPreventing crabgrass; Annual grassy and broadleaf weeds
Essential oils + vinegar sprayMedium-highNoBroadleaf weeds in garden beds (contact kill)
BoraxLowNo (avoid lawn)Weeds in pavement cracks only
Rubbing alcoholMediumNoYoung broadleaf weeds on pavement
Baking soda + waterLowNoYoung broadleaf seedlings
Boiling waterLowNoConcrete or walkway cracks; Young weeds in cracks and pavement

Important: No homemade recipe selectively targets weeds while leaving established grass unharmed. For broadleaf weed control in lawns, a selective herbicide is the right tool.

Vinegar and salt solution

Overall success: High
Best for: Young annual broadleaf weeds
Herbicide type: Post-emergent
Safe for grass: No

Horticultural vinegar (20%–30% acetic acid) combined with salt and dish soap is the strongest non-selective homemade weed killer widely available. It dehydrates plants and burns plant tissues, disrupting cell membranes.

“Natural does not automatically mean safe,” Mercer says. “Concentrated vinegar can burn skin and eyes, and salt can damage soil and surrounding plants even after the spray dries.”

Mercer says the biggest mistake people make is treating 20% horticultural vinegar like kitchen vinegar.

“It is strong enough to blister skin, injure eyes, harm soil life, and damage any plant it touches,” she explains. “Always wear gloves and eye protection and apply it carefully around desirable plants. Be careful using it on patios or driveways because repeated exposure can damage concrete.”

Adding salt can keep treated areas bare for months to several years by making the soil inhospitable, but it does not directly kill roots the way a systemic herbicide does.

“Salt lasts much longer in the soil than vinegar, up to several years, so only use it where you want nothing to grow, such as in driveway cracks or along hardscape edges,” Mercer warns. “Once salt builds up in a planting area, flushing it out can take a long time and is not always easy to correct.”

What you need:

  • 1 gallon of horticultural vinegar
  • 1 tablespoon of dish soap
  • 1 cup of table salt

Directions:

  1. Mix the ingredients until the solution is uniform.
  2. Apply with a garden sprayer. 

Important safety note: Since the solution contains a strong acid, cover your skin and eyes, and store the vinegar spray away from children and pets. Also, avoid inhaling its vapors by only handling it in open outdoor spaces.

Application tips:

  • Do: Apply to every weed leaf, as soon as weeds sprout, on a hot and dry day. Wear waterproof gloves and safety glasses.
  • Avoid: Using in garden beds, near turf, in rain or wind, or near people and pets.

Corn gluten meal

Pile of yellow corn gluten meal granules used as a natural fertilizer on a white surface
Corn gluten meal, a natural fertilizer and pre-emergent weed preventer. Photo Credit: Phu Thinh Co / Flickr / CC BY-SA 2.0
Overall success: Low to medium
Best for: Annual grassy weeds (including crabgrass) and broadleaf weeds 
Herbicide type: Pre-emergent
Safe for grass: Yes

Corn gluten meal is the only natural weed killer on this list that won’t damage your lawn. It interferes with root formation in germinating seeds while fertilizing grass with slow-release nitrogen.

“Corn gluten meal is a pre-emergent suppressant, so it must be applied when weeds are germinating from seed,” Mercer says. “It will not work on established weeds, and many common corn products, like cornmeal, corn flour, and cracked corn, do not have the right analysis to be weed suppressants.”

Effectiveness varies significantly by timing, application rate, and weather. The key is to apply before weeds germinate, and avoid applying right before heavy rain.

What you need:

  • Corn gluten meal (60% to 65% protein)

Directions:

  1. Use a fertilizer spreader to apply the granules.
  2. Gently water the lawn to activate, only applying about ¼-inch of water.

Application tips:

  • Do: Pull visible weeds before applying, calibrate the spreader, and apply evenly on established lawns.
  • Avoid: After overseeding, to new grass, to visible weeds, when the lawn is wet, before heavy rain, or overwatering.

Essential oils and vinegar spray

Overall success: Medium to high
Best for: Broadleaf weeds in garden beds and pavement cracks (not in lawns)
Herbicide type: Post-emergent
How it works: Dehydrating plants, killing microbes, damaging plant tissue
Safe for grass: No

This homemade weed killer recipe uses essential oils instead of straight vinegar, but it’s still a strong contact herbicide. Treat it like a pesticide and wear gloves and keep pets away until it’s dry.

Clove oil targets broadleaf weeds and soil microbes. Cinnamon oil is effective against redroot pigweed and wild mustard. Peppermint oil kills young weeds and prevents ryegrass seeds from germinating. White vinegar dehydrates plants and is most effective at broadleaf weed control. Finally, add dish soap so the formula sticks to your weeds.

What you need:

  • 10 drops of clove oil
  • 10 drops of peppermint oil
  • 10 drops of cinnamon oil
  • 4 cups of white distilled vinegar
  • 1 tablespoon of dish soap

Directions:

  1. Mix the ingredients until uniform.
  2. Apply with a sprayer.

Application tips:

  • Do: Shake the sprayer, store in a dark-colored spray bottle in a cool place, apply on a sunny day, and wear gloves.
  • Avoid: Using on turf, applying to wet weeds, spraying during heavy wind, right before a rainstorm, or letting it get on plants you want to keep.

Borax

Glass bowl filled with white borax powder on a blue background
A glass bowl of borax powder, commonly used as a natural weed killer. Photo Credit: Michelle / Adobe Stock
Overall success: Low
Best for: Occasional spot‑treatment of weeds in pavement cracks only
Herbicide type: Post-emergent
Safe for grass: No — avoid lawn application

Borax targets stubborn weeds using boron toxicity and sodium dehydration. Some homeowners use it to spot-treat their lawns, but this is a very bad idea.

Mercer says repeated use leads to lasting changes.

“Borax adds boron, a micronutrient that can be toxic if overapplied. These chemicals are best for weeds in pavement cracks, not in garden beds or anywhere you plan to plant later.”

What you need

  • 1 ¼ cups of Borax (laundry powder)
  • 1 gallon of hot water

Directions:

  1. Mix Borax with hot water until it completely dissolves. 
  2. Then, apply it with a sprayer.

Application tips:

  • Do: Apply early in the morning after the dew dries, apply a second round 2 weeks after the first application, wear safety glasses and long clothes.
  • Avoid: Getting it on desirable plants, applying to turf, or using near children or pets.

Rubbing alcohol

Bottle of isopropyl rubbing alcohol
Isopropyl rubbing alcohol, which can be used as a natural weed killer. Photo Credit: ajay_suresh / Flickr / CC BY 2.0
Overall success: Medium
Best for: Broadleaf weeds
Herbicide type: Post-emergent
Safe for grass: No

Diluted rubbing alcohol dehydrates weed tissue on contact. Use it only for driveway cracks and gravel, because repeated use can damage nearby plants and soil life. Don’t forget that rubbing alcohol is highly flammable.

What you need

  • 1 quart of water
  • 2 tablespoons of rubbing alcohol

Directions

  1. Mix the rubbing alcohol and water.
  2. Apply it with a garden sprayer.

Application tips:

  • Do: Apply with a cotton ball for precision on hot, sunny days. Wash it off immediately if any gets on the turf.
  • Avoid: Applying when weeds are wet or before a rainstorm.

Baking soda and water

Overall success: Low 
Best for: Young broadleaf weeds
Herbicide type: Post-emergent
How it works: Dehydrating plants, killing microbes, raising soil pH
Safe for grass: No

This mixture only harms plant parts that it touches. Typically, it only kills young broadleaf weeds, but it can cause decline in any plant. 

Baking soda is still a salt that can upset soil and cause problems if overused. Since salt dries out plants and soil, many homeowners hone in on this homemade weed-killer spray. Like other salt-based substances, baking soda can linger in soil for months.

What you need

  • 1 cup of baking soda
  • 1 gallon of water

Directions:

  1. Mix the solution until all the baking soda dissolves
  2. Then, apply it with a spray bottle

Application tips:

  • Do: Apply on a hot and sunny day and shake the bottle before applying.
  • Avoid: Applying if your soil is already salty, right before heavy rain, or to high pH soil.

Boiling water

Overall success: Low
Herbicide type: Post-emergent
Best for: Young weeds with shallow roots
Safe for grass: No

Boiling water is the easiest and cheapest homemade weed killer. It damages plant tissue but is non-selective and can harm any plant. It may permanently kill shallow-rooted weeds, but established perennials often regrow.

“Boiling water should be reserved for weeds in pavement cracks where there are no nearby roots you want to protect,” Mercer says.

“Occasional use on solid concrete or pavers is unlikely to cause much damage, but repeated use on asphalt, loose joints, or already weakened surfaces can lead to problems. The biggest hazard with boiling water, however, is the risk of splashing nearby plants or yourself,” she continues.

What you need:

  • Boiling water

Directions:

  1. Boil water.
  2. Pour it directly on unwanted weeds.

 Application tips:

  • Do: Apply with a tea kettle while the water is boiling, targeting small weeds in cracks.
  • Avoid: Splashing boiling water on yourself or desirable plants.

FAQs

Does homemade weed killer work on dandelions?

Most DIY sprays only damage the visible leaves. Dandelions have deep taproots, meaning they will likely regrow unless you manually dig out the root system or repeatedly smother them.

How long does a homemade weed killer take to work?

Strong contact solutions like vinegar and salt can wilt and kill visible weed foliage within 24 hours. Slower methods like baking soda may take several days to show results.

Is homemade weed killer safe for pets?

While ingredients like vinegar and salt are natural, concentrated horticultural vinegar and essential oils can irritate skin, eyes, and paws.

Always keep pets away until the treated area is completely dry. For salt-based recipes, keep pets away from treated soil for longer, since salt residue can linger and irritate paws even after the liquid dries.

Skip the spraying and call a pro

If pesky weeds are an eyesore in your lawn, it’s time to call a weed control pro. Since regular mowing is one of the best cultural practices for controlling weeds, we also recommend hiring a pro for routine lawn care.

Lawn Love connects you with qualified outdoor service experts. Our app makes it easy to find local pros with insurance and affordable rates. It only takes a couple of mouse clicks to make your lawn lovely and lush.

Main Image: A gardener spraying weed killer on a dandelion growing in a pathway. Photo Credit: dean / Adobe Stock

Adrian Nita

Adrian is a former marine navigation officer turned writer with more than four years of experience in the field. He loves writing about anything and everything related to lawn care and gardening. When he's not writing, you can find him working in his yard, constantly testing new lawn care techniques and products.